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HIV and Hepatitis C Co-infection

Education Packet

HIV and Hepatitis C Co-infection – This packet is a compilation of recent fact sheets and other resources. You may wish to customize it to meet the needs or interests of particular groups, such as event participants, providers, patients, clients, or the general public. So please feel free to distribute all or part of this packet as either a printout or PDF.


Fact Sheets, Infographics, and Briefs

HIV and Hepatitis C (HIVinfo) – This fact sheet describes what hepatitis C (HCV) is, how it is transmitted, the connection between HIV and HCV, and HCV prevention, testing, symptoms, and treatment.  Also available in Spanish.

HIV and Hepatitis B and Hepatitis C Coinfection ( – This web page in question-and-answer format includes information on hepatitis B and C transmission, prevention, and treatment, as well as recommended hepatitis testing for people with HIV.

People Coinfected with HIV and Viral Hepatitis (CDC) – This web page provides an overview of HIV co-infection with either hepatitis A, hepatitis B, or HCV. It also includes a discussion of hepatitis vaccination and testing, as well as links to guidelines and recommendations for the management of HIV and viral hepatitis co-infection.

HIV and Hepatitis C Coinfection (Department of Veterans Affairs) – This fact sheet in question-and-answer format provides basic information about HIV, HCV, and coinfection, together with information about the risk factors, prevention, transmission, and treatment of HIV-HCV coinfection. Tips for living a healthy life with coinfection are also provided.

Barriers to Curing Hepatitis C Virus Among Coinfected People with HIV (AETC National Coordinating Resource Center) – According to AETC, this infographic “addresses some of the barriers to curing HCV infection among co-infected people with HIV. It highlights provider, patient, and financial/systems barriers, provides information for HCV treatment initiation based on the latest treatment guidelines, and offers additional considerations to help health professionals navigate through some of the challenges outlined.


Guidelines and Recommendations

Viral Hepatitis Surveillance Report – United States, 2020, (CDC) – This report provides data on new diagnoses and mortality data related to hepatitis A (HAV), hepatitis B (HBV), and hepatitis C virus (HCV), as well as outcome data from CDC’s Perinatal Hepatitis B Prevention Program. An extensive slide set of data tables, graphs, and maps summarizing 2020 hepatitis surveillance is also available.

Hepatitis C Virus/HIV Coinfection ( – This section of the Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV includes recommendations for screening people living with HIV for HCV; providing antiretroviral therapy (ART) for HIV to co-infected persons; the potential for liver toxicity among co-infected persons receiving ART; and concurrent treatment of HIV and HCV. 

Patients with HIV/HCV Coinfection (American Association for the Study of Liver Diseases and Infectious Diseases Society of America) – This is a section of HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C. It includes tables of recommendations on managing interactions of the drugs used to treat HCV and HIV, as well as guidance regarding regimens not recommended for persons with HIV/HCV co-infection.


Curricula, Toolkits, and Other Educational Materials

HIV/HCV Co-infection: An AETC National Curriculum – This curriculum for healthcare providers and trainers of healthcare providers is designed “to increase their knowledge on HIV and HCV co-infection among people of color in the United States and its territories,” according to AETC. The curriculum has the following six core modules: epidemiology; prevention; screening, testing, and diagnosis; HCV treatment; recommendations for subpopulations of HIV/HCV co-infected persons; and addressing barriers for co-infected people of color.

Treatment of HCV in Persons with HIV Coinfection (University of Washington) – This self-study module provides background on HIV/HCV co-infection, a review of data on HCV treatment in people with HIV, recommended HCV treatment in persons with HIV co-infection, treatment of HIV in persons with HCV co-infection, drug interactions with HIV/HCV co-infection treatment, a summary of key points, and an extensive reference list.

Hepatitis C Prescriber Toolkit (TargetHIV, HRSA) – This toolkit has state-specific resources to help providers navigate the health coverage requirements that affect the prescription of HCV treatment. It includes information about prescribing restrictions; Ryan White HIV/AIDS Program AIDS Drug Assistance Program coverage; and Medicare coverage.

HIV in Pregnancy: Principles of Management and Care in 2022 (New England AETC, September 2022) – This webinar 1) reviews the latest clinical trials evidence about ART safety and efficacy in pregnancy and breastfeeding; 2) reviews principles of management of HBV/HCV coinfection in pregnancy; 3) synthesizes the data behind current intrapartum management for women living with HIV; and 4) reviews the efficacy, safety, and uptake of recommended HIV PrEP regimens in pregnancy.

IAS Update 2022 (New England AETC, August 2022) – This webinar summarizes significant findings and key updates from the 24th International AIDS Conference. Topics include: viral hepatitis, behavioral prevention, PrEP, antiretroviral therapy, and the HIV care continuum.

HIV/HCV Molecular Cluster Detection (Midwest AETC and others, May 2022) – These training slides provide an overview of molecular cluster detection, the steps needed to incorporate molecular cluster detection into a comprehensive HIV/HCV cluster detection outbreak response plan, and how it is implemented into the Wisconsin Department of Health Services’ work.

SSPs in Public Health – Mobile Innovations to Reach Rural Communities (New England AETC, April 2022) – This webinar examines existing data and public health challenges in HIV/HCV prevention and SSP access in rural areas and reviews innovative models for bringing services to most at-risk communities.

CROI 2022 Highlights: HIV Co-infections (Mountain West AETC, April 2022) – These training slides review highlights from CROI 2022 regarding HIV co-infections including hepatitis, tuberculosis, and COVID-19.

HIV & Viral Hepatitis: Highlights from CROI 2022 (South Central AETC, April 2022) – These training slides summarize highlights of the 2022 Conference on Retroviruses and Opportunistic Infections (CROI) related to HIV and viral hepatitis.

Myth-Busting HCV Treatment: Responsive HCV Screening, Treatment and Care (New England AETC, March 2022) – This part of the “Myth-Busting HCV Treatment” series focuses on identifying culturally responsive components of HCV treatment that successfully engage incarcerated populations for HCV screening, treatment, and care.

Connect to Cure – A Care Innovation Project (New England AETC, October 2021) – This seminar describes a multidisciplinary team’s experience providing innovative care for people at risk of drug and sex-related harms.

Myth-Busting HCV Treatment: Demystifying HCV Treatment in At-Risk Populations (New England AETC, January 2022) – This part of the “Myth-Busting HCV Treatment” series explores how advances in HCV treatment have affected the clinical management of people who inject drugs and persons with SUD. It also examines various monitoring strategies that can be used during HCV treatment and follow-up for hard-to-reach populations.

Myth-Busting HCV Treatment: Interdisciplinary HCV Screening, Treatment and Follow-up (New England AETC, December 2021) – This part of the “Myth-Busting HCV Treatment” series focuses on the role of an interdisciplinary team in completing the essential components of HCV treatment assessment, service delivery for marginalized populations, and outreach to individuals experiencing SUD.

Myth-Busting HCV Treatment: Integrated Models of HCV Care Delivery (New England AETC, November 2021) – This part of the “Myth-Busting HCV Treatment” series describes the process of care and patient outcomes in a practice serving young injection drug users with integrated HCV treatment services and opioid use disorder services.

ConnQuER HepC App: Educational and Care Companion App (New England AETC, October 2021) – This educational tool “is useful for patients, case managers, and community health workers. It is designed to inform about the clinical condition of hepatitis C and foster more efficient conversations between patients and healthcare providers.” It is part of the ConnQuer HepC project aimed at curing HCV among people of color with HIV.

Hepatitis C Toolkit Curriculum (Southeast AETC, September 2021) – The purpose of this training is to improve providers’ capacity to screen, medically manage, and provide advanced care for patients with HCV. The epidemiology of HCV, HIV, HBV, and other co-morbidities is also discussed.

International AIDS Society (IAS) Update 2021 Webinar (New England AETC, August 2021) – This webinar covers highlights from the virtual IAS 2021 Conference. Topics include: antiretroviral treatment for adults and adolescents; developments in HIV basic science; non-infection comorbidities of HIV and viral hepatitis; and COVID-19.

Supervised Consumption Sites Lecture (New England AETC, July 2021) – This lecture on supervised injection sites discusses the successes of safe consumption site programs and the benefits of establishing a program in the United States amidst an overdose epidemic.

Treating Hepatitis C Among People Who Use Drugs (Mountain West AETC, July 2021) – These training slides review the epidemiology of HCV among people who use drugs, review treatment as prevention, dispel myths about HCV treatment among people who use drugs, and discuss special considerations about HCV treatment for this population.

Clinically Relevant Drug Interactions with Direct Acting Antivirals (DAAs) (Mountain West AETC, June 2021) – These training slides cover the basic pharmacokinetic properties of DAAs, review interactions between DAAs and antiretroviral medications and non-HIV medications, and how to modify treatment for HCV or HIV.


The contents listed on this page are those of the author(s) and do not necessarily represent the official views of, nor an endorsement by, the New England AIDS Education and Training Center.